Abstract Background The rapid adoption of CRISPR technology has enabled biomedical researchers to conduct CRISPR-based genetic screens in a pooled format.The quality of results from such screens is heavily dependent on the selection of optimal screen design parameters, which also affects cost and scalability.However, the cost and effort of implemen
Drug resistance is one of the major causes of cancer-related deaths.Here, the authors using single cell RNA-seq of oral squamous cell carcinoma patient samples pre- and post-cisplatin DAMIANA treatment show that phenotypically homogenous cell populations display cell state BCAA XDM SPIKED POWDER BERRIES plasticity, with poised chromatin marks at me
A blind intrapulse modulation recognition based on energy focusing efficiency test was proposed, which can be used to estimate the modulation type under low signal to noise ratio (SNR) conditions.The observed signals were pre-processed by short Soccer - Clothing Junior Tops - Jackets time filter defined in frequency domain in order to improve the p